Kazuhiro Kawamura Selected Research

staurosporine aglycone (K252a)

12/2013	Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling.
1/2012	Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling.
3/2011	Brain-derived neurotrophic factor/tyrosine kinase B signaling regulates human trophoblast growth in an in vivo animal model of ectopic pregnancy.
7/2010	Inhibition of brain-derived neurotrophic factor/tyrosine kinase B signaling suppresses choriocarcinoma cell growth.
8/2009	Brain-derived neurotrophic factor promotes implantation and subsequent placental development by stimulating trophoblast cell growth and survival.

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Kazuhiro Kawamura Research Topics

Disease

8	Infertility (Sterility) 01/2022 - 10/2013
8	Neoplasms (Cancer) 12/2021 - 03/2005
3	Primary Ovarian Insufficiency 12/2020 - 02/2015
3	Choriocarcinoma 12/2013 - 07/2010
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 06/2015 - 10/2013
1	Body Weight (Weight, Body) 01/2022
1	Abnormal Karyotype 01/2022
1	Autoimmune Diseases (Autoimmune Disease) 01/2021
1	Amenorrhea 12/2020
1	Carcinogenesis 04/2020
1	Wilms Tumor (Wilm's Tumor) 01/2020
1	Mucoepidermoid Carcinoma 08/2016
1	Ewing Sarcoma (Sarcoma, Ewing) 06/2015
1	Breast Neoplasms (Breast Cancer) 02/2015
1	Cysts 01/2014
1	Neoplasm Metastasis (Metastasis) 12/2013
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 12/2013
1	Hydatidiform Mole (Molar Pregnancy) 08/2012
1	Female Infertility 07/2012
1	Sarcoma (Soft Tissue Sarcoma) 01/2012
1	Leiomyosarcoma 01/2012
1	Ectopic Pregnancy 03/2011
1	Fetal Weight 08/2009
1	Rupture 10/2006
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 09/2004
1	Male Infertility (Male Sterility) 02/2002
1	Weight Loss (Weight Reduction) 02/2002
1	Cryptorchidism (Undescended Testes) 02/2002

Drug/Important Bio-Agent (IBA)

5	staurosporine aglycone (K252a)IBA 12/2013 - 08/2009
5	Brain-Derived Neurotrophic Factor (BDNF)IBA 12/2013 - 07/2010
3	Pharmaceutical PreparationsIBA 12/2020 - 01/2020
3	Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric 12/2013 - 07/2010
3	Caspase 3 (Caspase-3)IBA 01/2012 - 07/2010
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2012 - 07/2010
2	AntralIBA 12/2020 - 02/2015
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2005
2	Tumor Biomarkers (Tumor Markers)IBA 12/2013 - 07/2010
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2012 - 03/2011
1	Biological ProductsIBA 01/2022
1	ResveratrolIBA 01/2022
1	bu-zhong-yi-qi-tangIBA 01/2022
1	CateninsIBA 04/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020
1	MTOR InhibitorsIBA 01/2020
1	Connective Tissue Growth FactorIBA 01/2020
1	Indicators and Reagents (Reagents)IBA 08/2016
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 08/2016
1	Phenobarbital (Luminal)FDA Link 02/2015
1	TensinsIBA 02/2015
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 02/2015
1	Firefly LuciferasesIBA 12/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2013
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 12/2013
1	CaspasesIBA 12/2013
1	trkB ReceptorIBA 08/2012
1	neurotropinIBA 01/2012
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2012
1	LigandsIBA 01/2012
1	deoxyuridine triphosphateIBA 01/2012
1	Methotrexate (Mexate)FDA LinkGeneric 03/2011
1	GonadotropinsIBA 10/2006
1	SurvivinIBA 03/2005
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 09/2004
1	Leucine (L-Leucine)FDA Link 09/2004
1	BOF 4272IBA 02/2002
1	Xanthine OxidaseIBA 02/2002
1	Allopurinol (Remid)FDA LinkGeneric 02/2002

Therapy/Procedure

9	Therapeutics 12/2021 - 07/2010
2	Radiotherapy 01/2021 - 06/2015
2	Lasers (Laser) 06/2015 - 10/2013
2	Drug Therapy (Chemotherapy) 06/2015 - 01/2012
1	Ovariectomy (Oophorectomy) 01/2018
1	Transplantation 11/2016
1	Cystectomy 01/2014
1	Intravenous Injections 12/2013
1	Autologous Transplantation 10/2013
1	Heterologous Transplantation (Xenotransplantation) 03/2011